What should be avoided when administering TPN to a patient?

When administering Total Parenteral Nutrition (TPN), it is critical to ensure the integrity and effectiveness of the nutrition being provided to the patient. TPN is a complex mixture that includes carbohydrates, proteins, fats, vitamins, and minerals, specifically formulated to meet a patient's nutritional needs when they cannot be fed orally or enterally.

Crushing sublingual tablets should be avoided as it can affect the pharmacokinetics of the medication. Sublingual tablets are specifically designed to dissolve under the tongue for quick absorption directly into the bloodstream. Altering the form of these tablets by crushing them can lead to improper absorption and may not provide the intended therapeutic effect. This is important because patients receiving TPN may require specific medications that must be absorbed in their intended manner to avoid complications.

In contrast, mixing TPN with other IV fluids can lead to precipitate formation and nutrient loss, and using a disconnected line can introduce risks such as air embolism or infection. Administering TPN rapidly poses a risk of fluid overload and hyperglycemia, both of which can lead to serious complications. Therefore, while all the listed scenarios have potential risks, the issue of altering the form of sublingual medications directly impacts their pharmacological effectiveness, which is why